One of the main problems with the mechano growth factor (MGF) is its short half-life as it breaks down within a few minutes. It is usually produced in the liver. Then, it travels into the bloodstream.
Scientists conducted different studies to increase the half-life of mechano growth factor, where they isolated and modified MGF by adding a compound. So, this marked the beginning of the Pegylated Mechano Growth Factor (PEG-MGF).
What Is It?
Pegylated Mechano Growth Factor (PEG-MGF) is a type of insulin-like growth factor 1 that is truncated and altered.
Studies show that PEG-MGF stimulates muscle cell proliferation. Some evidence suggests that PEG-MGF boosts immune function in terms of healing. The human subjects recover from wounds and other injuries more quickly than those who do not take PEG-MGF.
What Is It Used For?
As PEG-MGF activates muscle cell proliferation, it is used to help patients recover from sprains and strains after a surgical operation.
Athletes are always prone to these injuries, which typically require surgeries. But the healing process may take some time.
Studies in mice with a muscle injury showed fast healing. Experts believe PEG-MGF decreases specific inflammatory hormones and minimize the impact of oxidative stress, protecting the cells over time.
Here are the other benefits of PEG-MGF:
Repair Heart Muscles
The cells die in cardiac muscle during hypoxia, a condition in which a region of the body is deprived of oxygen.
Peptides like PEG-MGF may recruit stem cells to the damaged cardiac muscles to aid in regeneration and recovery after a heart attack. Further research is still needed.
Improve Dental Health
PEG-MGF is also used in dental applications for the past years. Studies in human periodontal ligament cells show that the peptide may increase the expression of MPP-1 and 2. It may also promote osteogenic differentiation, which helps repair the ligaments that attach our teeth to bone. Again, extensive studies are required.
Facilitate Bone Growth and Repair
When PEG-MGF was used in rabbits with serious bone injury, medical experts found that the peptide increased osteoblasts, the cells that form new bones.
The healing only took around four weeks. Usually, rabbits need six weeks to recover. With that, scientists study the peptide’s potential for human use in terms of bone healing. Let’s hope it will be a success.
What’s the Half-Life of PEG-MGF Now?
Megano growth factor only has around 5 or 7 minutes of half-life. But with the addition of Polyethylene glycol (PEG), its half-life can last up to 48 hours. Sometimes, it can reach 72 hours. That’s long.
Compared to other compounds, PEG does not bind to other substances in our system. It is usually excreted via urination. It is also administered using subcutaneous injections. So, medical supervision may be necessary for beginners and even experienced patients.
Who Is It For?
MGF-PEG may be ideal for those who have medical conditions requiring soft tissue repair following a heart attack, stroke, sarcopenia, or any exercise-related injury.
What are you waiting for? Look for peptides for sale online to avail discounts and other great deals.